Paclitaxel hypersensitivity
نویسندگان
چکیده
منابع مشابه
Hypersensitivity reaction to parenteral nutrition after severe hypersensitivity reaction to paclitaxel: a case report
Paclitaxel, an anti-microtubule chemotherapeutic agent, is known for hypersensitivity reactions. Hypersensitivity reactions associated with paclitaxel may be secondary to its vehicle, Cremophor EL rather than the paclitaxel itself. In contrast, hypersensitivity reactions to parenteral nutrition are uncommon. Both the lipid component and multivitamin have been implicated in hypersensitivity reac...
متن کاملSuccessful treatment with nab-paclitaxel after hypersensitivity reaction to paclitaxel and docetaxel☆
•First case report of successfully treating severe paclitaxel and docetaxel hypersensitivity reaction with nab-paclitaxel•We demonstrated that nab-paclitaxel is a safe taxane chemotherapy treatment option for patients who could not tolerate paclitaxel or docetaxel.
متن کاملUniversal tolerance of nab-paclitaxel for gynecologic malignancies in patients with prior taxane hypersensitivity reactions
OBJECTIVE To report on the incidence of nab-paclitaxel hypersensitivity reactions (HSRs) in patients with prior taxane HSR. METHODS From 2005 to 2015, all patients who received nab-paclitaxel for a gynecologic malignancy were identified. Chart abstraction included pathology, prior therapy, indication for nab-paclitaxel, dosing, response, toxicities including any HSR, and reason for discontinu...
متن کاملAbraxane for the treatment of gynecologic cancer patients with severe hypersensitivity reactions to paclitaxel.
BACKGROUND Paclitaxel is used in the treatment of most gynecologic malignancies. It is solubilized in Cremophor EL, a polyoxyethylated castor oil agent responsible for the high rate of paclitaxel-associated hypersensitivity reactions. Abraxane, a newer, Cremophor-free form of albumin bound paclitaxel has demonstrated an activity and an improved toxicity profile in breast and lung cancers. CAS...
متن کاملHypersensitivity reaction studies of a polyethoxylated castor oil-free, liposome-based alternative paclitaxel formulation
The commercial drug paclitaxel (Taxol) may introduce hypersensitivity reactions associated with the polyethoxylated castor oil-ethanol solvent. To overcome these problems, we developed a polyethoxylated castor oil-free, liposome-based alternative paclitaxel formulation, known as Lipusu. In this study, we performed in vitro and in vivo experiments ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cancer Research, Statistics, and Treatment
سال: 2020
ISSN: 2590-3233
DOI: 10.4103/crst.crst_8_20